The collection is contained in twenty two boxes comprised of three series. The first series consists of materials related to Clyda Rent's inauguration in 1989. The second pertains to the university's application for National Landmark status, and the last documents the Ayers Case.

Series 1: The collection is contained in five folders which are contained in one box. Most of the collection is news clippings of Rent's inauguration in 1989.

Series 2: In 1990 a second application was filed with the National Park Service to have the front of the MUW campus designated as a National Historic Landmark. This was a collaboration between Clyda Stokes Rent, The Mississippi Department of Archives and History, And Sally and Bruce McMillan. The first application was filed in 1965. Both were rejected. The collection is contained in twenty folders which are contained in one box. Most of the collection is documentation on the History of the institution thought the years and history and floor plans of the buildings that are listed on the National Register of Historic Places.

Series 3: Jacob Ayers filed a class action lawsuit vs. the Governor of Mississippi, the Board of Trustees for Institutions of Higher Learning (IHL), the Commissioner of Higher Education, and others in the five historically white public Mississippi universities in 1975, alleging that the state maintained de facto segregation in its universities by inadequately funding historically black universities, a violation of the Equal Protection clause. The case, Ayers v. Allain, was decided against the plaintiffs in the US District Court, but overturned on appeal and heard by the US Supreme Court in 1992. The court found that the state had not done enough to dismantle its old segregated university system.

From there the case was remanded to the district court, where the state proposed merging Mississippi University for Women with Mississippi State University, and Mississippi Valley State University with Delta State University, among other changes. In March 1995, presiding judge Neal B. Biggers Jr. of the US District Court for the Northern District of Mississippi rejected the proposed mergers, allowing the two universities to continue operations. An alternative set of remedies was settled upon, and the case was adjourned in 2002.

The collection includes the legal documents required by all universities in Mississippi involved in Ayers case to house in their libraries for public reference, which originally appear to have come from the office of Dr. Rent. Her notes also feature prominently. This series also includes grant information from the same period. Three boxes include materials that appear to have been brought into Dr. Rent’s office from the offices of Admissions, Academic Affairs, and Financial Affairs.